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Olmesartan Medoxomil+amlodipine

About Olmesartan Medoxomil+amlodipine

Amlodipine+olmesartan Medoxomil is a combination of medication containing blood pressure-lowering medicines primarily used to treat high blood pressure. Amlodipine+olmesartan Medoxomil is used alone or in combination with other blood pressure-lowering medications. Hypertension or high blood pressure is a chronic condition in which the blood's force against the artery wall is high. As a result, it leads to heart disease, irregular heartbeat, and other complications.

Amlodipine+olmesartan Medoxomil contains Olmesartan (angiotensin receptor blocker) and Amlodipine (calcium channel blocker). Olmesartan works by blocking the hormone angiotensin, thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Amlodipine, on the other hand, acts by relaxing the blood vessels. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, both help lower high blood pressure, reducing heart attack or stroke chances. 

You can take Amlodipine+olmesartan Medoxomil with food or without food with a glass of water. Do not chew, bite, or break it. Your doctor will advise you on how often you should take your tablets based on your medical condition. In some cases, you may experience headaches, drowsiness, ankle swelling, nausea, dizziness, and low blood pressure. Most of these side effects of Amlodipine+olmesartan Medoxomil do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. It is advisable to drink plenty of fluids while taking Amlodipine+olmesartan Medoxomil.

Try not to stop taking Amlodipine+olmesartan Medoxomil on your own. Inform your doctor, and your dose might be gradually lowered to avoid a rise in blood pressure and increase the risk of heart disease and stroke. Inform your doctor if you are suffering from kidney, liver, heart disease, or diabetes. If you are pregnant or breastfeeding, please tell your doctor, as it is not recommended in pregnancy. It should not be given to children less than 12 years of age. Do not use Amlodipine+olmesartan Medoxomil if you have low blood pressure (hypotension) or cardiogenic shock (sudden stopping blood flow to the heart). Please tell your doctor if you are taking any other medicines or are allergic to the Amlodipine+olmesartan Medoxomil. Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling. Grapefruit juice and St. John's wort plant should not be consumed when taking Amlodipine+olmesartan Medoxomil as it is contraindicated.

Uses of Olmesartan Medoxomil+amlodipine

Treatment of Hypertension (high blood pressure).

Medicinal Benefits

Amlodipine+olmesartan Medoxomil contains Olmesartan (angiotensin receptor blocker) and Amlodipine (calcium channel blocker). Olmesartan works by blocking the hormone angiotensin, thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Amlodipine, on the other hand, acts by relaxing the blood vessels. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, both help lower high blood pressure, reducing future heart attack or stroke chances.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Olmesartan Medoxomil+amlodipine

  • Headaches
  • Drowsiness
  • Ankle swelling
  • Nausea
  • Dizziness
  • Low blood pressure

Drug Warnings

Amlodipine+olmesartan Medoxomil should not be given to the people allergic to Amlodipine+olmesartan Medoxomil or may of its ingredients. If you have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease, liver disease, are pregnant, or planning to get pregnant and breastfeeding women; do not take Amlodipine+olmesartan Medoxomil. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem). Amlodipine+olmesartan Medoxomil can pass into breast milk, but its effect on the baby is not known. So, it is better to tell your doctor if you are taking Amlodipine+olmesartan Medoxomil and breastfeeding. Grapefruit juice and St. John's wort plant should not be consumed when taking Amlodipine+olmesartan Medoxomil as it is contraindicated. Drinking alcohol while using Amlodipine+olmesartan Medoxomil can cause you to have low blood pressure, so avoid alcoholic beverages.

Drug Interactions

Drug-Drug Interactions: Amlodipine+olmesartan Medoxomil may interact with high blood pressure lowering pills (metoprolol, ramipril, hydrochlorothiazide), drugs used to control lipid levels in the blood (atorvastatin, simvastatin), medicines to treat erectile dysfunction (sildenafil), antibiotics (erythromycin, rifampin), antifungal (itraconazole, ketoconazole), anti-HIV drugs (ritonavir), anti-epilepsy medicines (carbamazepine, phenytoin, phenobarbital, primidone), immune-suppressing drugs (cyclosporine, tacrolimus) and painkillers (ibuprofen, aspirin).

Drug-Food Interactions: Amlodipine+olmesartan Medoxomil may interact with grapefruit, grapefruit juices, and St. John’s wort (a plant used to treat depression). Hence it should not be taken with Amlodipine+olmesartan Medoxomil.

Drug-Disease Interactions: Amlodipine+olmesartan Medoxomil should not be given to people with cardiogenic shock (when the heart fails to pump required blood to the body), heart valve problem (stenosis), low blood pressure (hypotension), liver disease, or heart failure.

Drug-Drug Interactions Checker List:

  • METOPROLOL
  • RAMIPRIL
  • HYDROCHLOROTHIAZIDE
  • ATORVASTATIN
  • SIMVASTATIN
  • SILDENAFIL
  • ERYTHROMYCIN
  • RIFAMPICIN
  • ITRACONAZOLE
  • KETOCONAZOLE
  • RITONAVIR
  • CARBAMAZEPINE
  • PHENYTOIN
  • PHENOBARBITAL
  • PRIMIDONE
  • CYCLOSPORINE
  • TACROLIMUS
  • IBUPROFEN
  • ASPIRIN
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      You are recommended not to consume alcohol along with Amlodipine+olmesartan Medoxomil to avoid unpleasant side effects.

    • Safety Warning

      Pregnancy

      caution

      Amlodipine+olmesartan Medoxomil contains category C (amlodipine) and category D (telmisartan) as category D is a high risk, so it should not be taken during pregnancy.

    • Safety Warning

      Breast Feeding

      caution

      Amlodipine+olmesartan Medoxomil is not recommended in breastfeeding mothers. It is excreted into milk in small amounts and is cleared slowly. It can accumulate in infants, especially newborns or preterm infants. Lactation might also be suppressed due to the effect of Amlodipine+olmesartan Medoxomil.

    • Safety Warning

      Driving

      caution

      Driving after taking Amlodipine+olmesartan Medoxomil is not recommended as it may occasionally cause drowsiness or fatigue.

    • Safety Warning

      Liver

      caution

      Amlodipine+olmesartan Medoxomil to be taken with caution, especially if you have a liver disease history. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

    • Safety Warning

      Kidney

      caution

      Amlodipine+olmesartan Medoxomil to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

    • Safety Warning

      Children

      unsafe

      Use of Amlodipine+olmesartan Medoxomil in children less than 12 years of age is not recommended as the safety and efficacy of Amlodipine+olmesartan Medoxomil in these age groups have not yet been established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Keep your weight under control with a BMI of 19.5-24.9.

    • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.

    • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.

    • Limit sodium chloride (table salt) intake in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.

    • If you are taking alcohol, then only one serving for women and two servings for men is advisable.

    • Quitting smoking is the best strategy to lower the risk of heart disease.

    • Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.

    • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.

    • Try to include heart-healthy omega-3 fatty acids-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to help lower your elevated blood pressure.

    Patients Concern

    Disease/Condition Glossary

    High blood pressure: It is the measurement of the force that our heart uses to pump blood to all parts of the body. Hypertension is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor. Systolic pressure is the pressure with which the heart pumps blood out. On the other hand, diastolic pressure is when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg, and diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.

    FAQs

    Amlodipine+olmesartan Medoxomil is used to treat Hypertension (high blood pressure).

    No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend discontinuing it.

    Amlodipine+olmesartan Medoxomil can be safely taken as long as your doctor prescribes it. Conditions such as high blood pressure are life-long conditions, and one should not abruptly discontinue it without discussing it with a doctor.

    Amlodipine+olmesartan Medoxomil contains Olmesartan (angiotensin receptor blocker) and Amlodipine (calcium channel blocker). Olmesartan works by blocking the hormone angiotensin, thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Amlodipine, on the other hand, acts by relaxing the blood vessels. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, both help lower high blood pressure, reducing heart attack or stroke chances.

    Yes, Amlodipine+olmesartan Medoxomil is contraindicated in people with known allergies to any of this medicine's components. It should be used with caution in people with liver impairment. It should also be avoided in women who are in the second and third trimesters of their pregnancy.

    unlikely that Amlodipine+olmesartan Medoxomil affects fertility in men or women. However, there's not enough evidence to say for certain. For the best advice, consult your doctor.

    Yes, Amlodipine+olmesartan Medoxomil contains amlodipine, which is known to cause ankle swelling upon long-term use. Please try to keep your feet up when sitting for long hours. If the problem persists still, consult your doctor and do as advised.

    High blood pressure during pregnancy is called 'Pregnancy-induced hypertension (PIH). It is harmful to both the baby and the mother. In the mother, very high blood pressure can cause seizures (fits), headache, swelling of the feet, kidney damage, and a higher risk of bleeding during pregnancy and delivery. This can also affect the baby by causing abnormal fetal heart rate, risk of stillbirth, and a small baby. So, during pregnancy, you should have regular blood pressure monitoring. Visit your Obstetrician if you have any concerns related to blood pressure during pregnancy.

    Before starting Amlodipine+olmesartan Medoxomil, it's crucial to have a thorough consultation with your doctor. Share your comprehensive medical history, including any existing conditions or past illnesses. Also, provide a detailed list of your medications, vitamins, and supplements. Inform your doctor about any medication allergies or sensitivities. Additionally, discuss your lifestyle habits, such as smoking, alcohol consumption, or recreational drug use. If you're pregnant, breastfeeding, or planning to become pregnant, be sure to disclose this information. This will enable your doctor to determine whether Amlodipine+olmesartan Medoxomil suits you and provide personalized care.

    Take Amlodipine+olmesartan Medoxomil precisely as prescribed by your doctor. The typical dosage is once daily, but your doctor may adjust the frequency based on your needs. To ensure effective treatment, follow your doctor's instructions regarding the best time of day to take Amlodipine+olmesartan Medoxomil. This may depend on your daily routine, other medications you're taking, and your medical condition. Be sure to ask your doctor if you have any questions or concerns about when to take Amlodipine+olmesartan Medoxomil.

    After starting Amlodipine+olmesartan Medoxomil, you can expect to start feeling better within 8 hours as your blood pressure begins to decrease. Within 1 week, you will start to feel the full effects of Olmesartan, with your blood pressure lowering further. As Amlodipine reaches its full effect in 3-4 weeks, your blood vessels relax, and blood flow improves. Finally, within 2-8 weeks, you'll likely experience the maximum benefit, with your blood pressure well-controlled and any related symptoms improved, helping you feel your best.

    It's important to take Amlodipine+olmesartan Medoxomil at the same time every day, as prescribed by your doctor. This helps maintain consistent levels of the medication in your body and ensures it works effectively. While you can take Amlodipine+olmesartan Medoxomil at any time of day, it's best to take it at a time that fits your daily routine.

    In some cases, you may experience headaches, drowsiness, ankle swelling, nausea, dizziness, and low blood pressure. Most of these side effects of Amlodipine+olmesartan Medoxomil do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.

    While using Amlodipine+olmesartan Medoxomil, consider making lifestyle changes to help manage your blood pressure and overall health. Maintain a healthy weight, exercise for at least 30 minutes a day, and eat a balanced diet rich in whole grains, fruits, vegetables, and low-fat dairy products. Limit your sodium intake and alcohol consumption, and quit smoking if you haven't already. Manage stress through mindfulness practices and social support, and monitor your blood pressure daily. Additionally, include omega-3-rich foods in your diet and use low-fat oils like olive, soybean, canola, and coconut oil for cooking. Remember to consult your doctor for personalized advice on making these lifestyle changes to ensure you're taking the best care of your health.

    Amlodipine+olmesartan Medoxomil may cause weight gain in some individuals, although it is not a common side effect. This is because Amlodipine can lead to fluid retention, while Olmesartan can increase potassium levels, resulting in increased water retention and weight gain. However, the weight gain is usually minimal. If you're concerned, your doctor can help you monitor your weight, adjust your diet and exercise routine, and explore alternative medications if needed.

    The serious side effects of Amlodipine+olmesartan Medoxomil include bloating or swelling of the face, arms, hands, lower legs, or feet and rapid weight gain, which occurs more commonly. Less common serious side effects include fast, irregular, pounding, or racing heartbeat or pulse, and unusual tiredness or weakness. If you experience any of these side effects, seek medical attention immediately.

    Amlodipine+olmesartan Medoxomil is unlikely to affect fertility or sex life in men or women. Still, the current evidence is insufficient to confirm this. To get personalized advice, consult your doctor.

    Take Amlodipine+olmesartan Medoxomil exactly as prescribed by your doctor to manage your high blood pressure (hypertension). This is a long-term treatment, which means you'll need to take it continuously for an extended period. Regular check-ups with your doctor are crucial to monitor your blood pressure, adjust your dosage as needed, and ensure Amlodipine+olmesartan Medoxomil works effectively and safely for you. Following your doctor's instructions and attending regular check-ups can effectively manage your high blood pressure and reduce the risk of related health issues.

    Take the missed dose as soon as you remember, unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.

    Do not consume alcohol along with Amlodipine+olmesartan Medoxomil to avoid unpleasant side effects. If you have any concerns regarding this consult your doctor.

    If you notice side effects while taking Amlodipine+olmesartan Medoxomil, they will usually be mild and temporary and will go away on their own as your body adjusts. However, if the side effects are severe, persistent, or worsen over time, it's important to consult your doctor for personalized advice and care.

    Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding. They will help you understand the potential risks and benefits of taking Amlodipine+olmesartan Medoxomil during this time. It's essential to prioritize your and your baby's health and well-being.

    Consult your doctor or pharmacist before taking any other medicines while on Amlodipine+olmesartan Medoxomil. They will help you understand potential interactions and ensure safe combined use. Some medicines may interact with Amlodipine+olmesartan Medoxomil, so it's essential to disclose all medications, supplements, and vitamins you're taking to avoid potential adverse effects.

    You can take Amlodipine+olmesartan Medoxomil with or without food. However, taking it with a meal is preferred to minimize stomach upset and dizziness. Taking it with food can help your body absorb the medication better.

    The side effects of Amlodipine+olmesartan Medoxomil include headaches, drowsiness, ankle swelling, nausea, dizziness, and low blood pressure. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, contact your doctor.

    Available Medicines for

    Olmesartan Medoxomil+amlodipine

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